Effects of Ozone on Spinal Cord Recovery via the Wnt/ Β-Catenin Pathway Following Spinal Cord Injury in Rats.

Tural Emon S., Uslu S., Ilgaz Aydinlar E., Irban A., İNCE Ü., Orakdogen M., ...Daha Fazla

Turkish neurosurgery, cilt.27, sa.6, ss.946-951, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5137/1019-5149.jtn.17508-16.1
  • Dergi Adı: Turkish neurosurgery
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.946-951
  • Anahtar Kelimeler: Beta-catenin, Ozone therapy, Rat, Spinal cord injury, Wnt pathway, THERAPY
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

AIM: At the cellular level, spinal cord injury (SCI) provokes an inflammatory response that generates substantial secondary damage within the spinal cord but may also contribute to its repair. Besides intracellular antioxydant increase after exactly estimated oxidative stress; oxygen formation and transport is also advanced by ozone. The Wnt family of proteins contributes to the development of the nervous system, influencing cell proliferation. In the present study we evaluated the effect of ozone on spinal cord injury in rats.