Systematic review and meta-analysis of within-subject and between-subject biological variation estimates of 20 haematological parameters

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COSKUN A., Braga F., Carobene A., Tejedor Ganduxe X., Aarsand A. K., Fernandez-Calle P., ...More

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol.58, no.1, pp.25-32, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 58 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.1515/cclm-2019-0658
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.25-32
  • Keywords: biological variation, erythrocyte, haemoglobin, leukocyte, meta-analysis, platelets, LIFE-SPAN, PERFORMANCE SPECIFICATIONS, EUROPEAN FEDERATION, CLINICAL-CHEMISTRY, CRITICAL-APPRAISAL, IN-VITRO, CHECKLIST
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Background: Interpretation of the complete blood count (CBC) parameters requires reliable biological variation (BV) data. The aims of this study were to appraise the quality of publications reporting BV data for CBC parameters by applying the BV Data Critical Appraisal Checklist (BIVAC) and to deliver global BV estimates based on BIVAC compliant studies.