Effects of peroxisome proliferator activated receptor gamma (PPAR gamma) agonist on fasting model applied neuron cultures

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Pinarbasi A., Pak M., Kolay M., ÖZ ARSLAN D., Aksungar F.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.47, sa.1, ss.41-48, 2022 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1515/tjb-2021-0104
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, Food Science & Technology Abstracts, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.41-48
  • Anahtar Kelimeler: fasting, ketone bodies, neuron cultures, pioglitazone, PPAR gamma, MITOCHONDRIAL-FUNCTION, COMPLEX I, MACROPHAGES, EXPRESSION, BODIES, TARGET
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Objectives: Peroxisome proliferator activated receptor gamma (PPAR gamma) agonists used for the treatment of Diabetes Mellitus (DM), has important roles on the regulation of metabolism including ketogenesis in fasting and low glucose states. Recently PPAR gamma was proven to have antioxidant and anti-inflammatory effects on neuronal cells.