Akademik Veri Yönetim Sistemi
ECCMID 2023, Kobenhavn, Danimarka, 15 - 18 Nisan 2023, ss.1-2
Background
Streptococcus pneumoniae is the leading cause of community-acquired pneumonia in adults. Cases of co-infection with Influenza may end in synergistic lethality, however, the relationship between SARS-CoV-2 and pneumococcal co-infection is unknown for clinical course. Therefore, serotype surveillance is of great importance for vaccination strategies developed to prevent pneumococcal diseases. The aim of this study is to determine the serotype distribution and antibiotic susceptibility of S. pneumoniae strains isolated from respiratory tract specimens of patients with suspected CAP (Community Acquired Pneumoniae) during the pandemic period.
Material/Method
S. pneumoniae strains isolated from tracheal aspirates and sputum were stored at -80 degrees in Acıbadem Hospital Central Laboratory (Acıbadem Labmed) before analysis. Strains were identified by the presence of alfa hemolysis, optochin susceptibility test and/or bile solubility test. Then, the serotype distribution of these isolates was determined by the capsule swelling (Quellung) reaction using group factor serums from Statens Serum Institute (Denmark, Copenhagen) in Acıbadem Central Laboratory and their antibiotic susceptibility was analyzed using E-test against penicillin, cefotaxime, erythromycin and quinolones according to EUCAST (The European Committee for Antimicrobial Susceptibility Testing) criteria.
Results
Forty-one of 131 S.pneumoniae strains obtained from sputum and tracheal aspirate could be revived. The most common serotypes were 1,9V and 19A, followed by 18C,4,3, 6A, 7F, 18F, 19F, 6B, 14,15B,20 and 23 F.
When antibiotic susceptibilities were examined, no resistance was found to penicillin and vancomycin. Erythromycin, clindamycin, levofloxacin and moxifloxacin resistance were found to be 63%, 44%, 9.75% and 9.75%, respectively.