Does "Cerebellar Liponeurocytoma" Always Reflect an Indolent Biological Behaviour?: An Unusual Case With Review of The Literature


Sav A., KARABAĞLI P., Deda H.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.29, no.2, pp.362-367, 2012 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Review
  • Volume: 29 Issue: 2
  • Publication Date: 2012
  • Title of Journal : JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Page Numbers: pp.362-367

Abstract

A rare tumor, cerebellar liponeurocytoma is classified into glioneuronal tumors under the 2000 World Health Organization (WHO) classification of tumors of the central nervous system. The current 2007 WHO classification assigns grade II to the cerebellar liponeurocytoma. Tumors are predominantly localized in cerebellar hemispheres, and the second most common location is the vermis. In the report, an unusual case of cerebellar liponeurocytoma was presented with clinically and histologically aggresive features. In future tumor classification, it should be considered that its biologic behavior is not as indolent as suggested by current literature. This tumor should be regarded as an uncertain malignant potential lesion when mitoses are present and the MIB-1 positive cells are more than 10%.