Genotoxicity study of high aspect ratio silver nanowires


Charehsaz M., Coskun S., ÜNALAN H. E. , Reis R., Helvacioglu S., Giri A. K. , ...More

TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, vol.99, no.5-6, pp.837-847, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 99 Issue: 5-6
  • Publication Date: 2017
  • Doi Number: 10.1080/02772248.2016.1276581
  • Journal Name: TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.837-847
  • Keywords: Silver nanowires, mutagenicity, in vivo chromosomal aberration test, Ames test, IN-VITRO, NANOPARTICLES, CELLS, MITOCHONDRIA, INFLAMMATION, GENERATION, RESPONSES, TOXICITY, LENGTH, VIVO
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

The genotoxicity potential of silver nanowires synthesized via the solution-based polyol method has been investigated. They were found to be non-mutagenic in three Salmonella strains and were not genotoxic in a clastogenicity assay in mice. Residual surfactant was found to have an effect on the toxicological properties of the nanowires by increasing the rate of Ag+ release. Residual surfactant can be easily degraded via a UV treatment.