Correlation between H-1 MRS and memory before and after surgery in mesial temporal lobe epilepsy with hippocampal sclerosis

Hanoglu L., ÖZKARA Ç., Keskinkilic C., Altin U., Uzan M., Tuzgen S., ...More

EPILEPSIA, vol.45, no.6, pp.632-640, 2004 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 6
  • Publication Date: 2004
  • Doi Number: 10.1111/j.0013-9580.2004.54302.x
  • Journal Name: EPILEPSIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.632-640
  • Keywords: H-1 MRS, memory, temporal lobe epilepsy, hippocampal sclerosis, surgery, MAGNETIC-RESONANCE-SPECTROSCOPY, VERBAL MEMORY, NEUROPSYCHOLOGICAL CHANGE, LATERALIZATION, NORMALIZATION, VOLUMETRY, LOBECTOMY, ADEQUACY, TESTS
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Purpose: Proton magnetic resonance spectroscopy (H-1 MRS). which can demonstrate neuronal loss and gliosis, may be used as a sensitive tool for lateralization of temporal lobe epilepsy (TLE). Although the correlation between the memory functions and H-1 MRS has been investigated, its predictive value after surgery has not been studied previously. This Study evaluated memory and H-1 MRS values of medically intractable patients with mesial TLE and hippocampal sclerosis (MTLE-HS) before and after selective amygdalohippocampectomy (SAH).