Correlation between H-1 MRS and memory before and after surgery in mesial temporal lobe epilepsy with hippocampal sclerosis
EPILEPSIA, vol.45, no.6, pp.632-640, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 45 Issue: 6
- Publication Date: 2004
- Doi Number: 10.1111/j.0013-9580.2004.54302.x
- Journal Name: EPILEPSIA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.632-640
- Keywords: H-1 MRS, memory, temporal lobe epilepsy, hippocampal sclerosis, surgery, MAGNETIC-RESONANCE-SPECTROSCOPY, VERBAL MEMORY, NEUROPSYCHOLOGICAL CHANGE, LATERALIZATION, NORMALIZATION, VOLUMETRY, LOBECTOMY, ADEQUACY, TESTS
- Acibadem Mehmet Ali Aydinlar University Affiliated: No
Abstract
Purpose: Proton magnetic resonance spectroscopy (H-1 MRS). which can demonstrate neuronal loss and gliosis, may be used as a sensitive tool for lateralization of temporal lobe epilepsy (TLE). Although the correlation between the memory functions and H-1 MRS has been investigated, its predictive value after surgery has not been studied previously. This Study evaluated memory and H-1 MRS values of medically intractable patients with mesial TLE and hippocampal sclerosis (MTLE-HS) before and after selective amygdalohippocampectomy (SAH).