Correlation between H-1 MRS and memory before and after surgery in mesial temporal lobe epilepsy with hippocampal sclerosis

Hanoglu L., Ozkara C., Keskinkilic C., Altin U., Uzan M., Tuzgen S., ...More

EPILEPSIA, vol.45, no.6, pp.632-640, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 6
  • Publication Date: 2004
  • Doi Number: 10.1111/j.0013-9580.2004.54302.x
  • Title of Journal : EPILEPSIA
  • Page Numbers: pp.632-640


Purpose: Proton magnetic resonance spectroscopy (H-1 MRS). which can demonstrate neuronal loss and gliosis, may be used as a sensitive tool for lateralization of temporal lobe epilepsy (TLE). Although the correlation between the memory functions and H-1 MRS has been investigated, its predictive value after surgery has not been studied previously. This Study evaluated memory and H-1 MRS values of medically intractable patients with mesial TLE and hippocampal sclerosis (MTLE-HS) before and after selective amygdalohippocampectomy (SAH).