Secondary metabolites from Scutellaria albida L. ssp. velenovskyi (Rech. f.) Greuter & Burdet

Matsa M., Bardakci H., Gousiadou C., Kirmizibekmez H., Skaltsa H.

BIOCHEMICAL SYSTEMATICS AND ECOLOGY, cilt.83, ss.71-76, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 83
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.bse.2019.01.006
  • Dergi Adı: BIOCHEMICAL SYSTEMATICS AND ECOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.71-76
  • Anahtar Kelimeler: Scutellaria albida L. ssp. velenovskyi, S. albida group, Iridoid glycosides, Flavonoids, Phenylethanoid glycosides, Acetogenic glycoside, PHENOLIC-COMPOUNDS, AERIAL PARTS, GLYCOSIDES, IRIDOIDS, CONSTITUENTS, ROOTS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Fourteen compounds (Fig.1) were isolated from the aerial parts of Scutellaria albida L. ssp. velenovskyi (Rech. f.) Greuter & Burdet, including four iridoids (1-4) catalpol, macfadienoside, mussaenosidic acid, albidoside; four flavonoids (5-8) hispidulin 7-O-beta-D-glucuronide, scutellarin, xanthomicrol, eriodictyol; four phenylethanoid glycosides (9-12) verbascoside, leucosceptoside A, martynoside, 2-(3-hydroxy-4-methoxy-phenyl)-ethyl-1-O-beta-D-glucopyranoside; the sugar ester 6'-beta-D-glucopyranosyl-E-p-coumarate (13), as well as the acetogenic glucoside (Z)-3-hexenyl-1-O-beta-D-glucopyranosyl-(1 -> 2)-beta-D-glucopyranoside (14). The structures of the isolates were established by means of NMR and HRMS spectral analyses. This is the first phytochemical study on S. velenovskyi and the first report of an acetogenic glycoside in the genus Scutellaria L. A chemical review on the isolated secondary metabolites in this study has been carried out. The chemotaxonomic value of the isolates is also discussed. Based on the literature data, the analysis revealed that the chemical profile of S. velenovskyi is close to that of the taxa belonging to the S. albida group.