Within-subject and between-subject biological variation estimates of 21 hematological parameters in 30 healthy subjects


Coskun A. , Carobene A., KİLERCİK M. , SERTESER M. , Sandberg S., Aarsand A. K. , ...More

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol.56, no.8, pp.1309-1318, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 8
  • Publication Date: 2018
  • Doi Number: 10.1515/cclm-2017-1155
  • Title of Journal : CLINICAL CHEMISTRY AND LABORATORY MEDICINE
  • Page Numbers: pp.1309-1318
  • Keywords: biological variation, complete blood count, hematology, preanalytical phase, REFERENCE CHANGE VALUES, CLINICAL-CHEMISTRY, EUROPEAN FEDERATION, LABORATORY MEDICINE, CRITICAL-APPRAISAL, SAMPLES, CHECKLIST, REVEALS, PROJECT, SERUM

Abstract

Background: The complete blood count (CBC) is used to evaluate health status in the contexts of various clinical situations such as anemia, infection, inflammation, trauma, malignancies, etc. To ensure safe clinical application of the CBC, reliable biological variation (BV) data are required. The study aim was to define the BVs of CBC parameters employing a strict protocol.