International randomized phase 2 study on the addition of docetaxel to the combination of cisplatin and 5-fluorouracil in the induction treatment for nasopharyngeal carcinoma in children and adolescents


Casanova M., Ozyar E. , Patte C., Orbach D., Ferrari A., Veyrat-Follet C., et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY, cilt.77, ss.289-298, 2016 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 77 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s00280-015-2933-2
  • Dergi Adı: CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • Sayfa Sayısı: ss.289-298

Özet

Nasopharyngeal carcinoma (NPC) is a rare but aggressive malignancy in children and adolescents. An international, randomized phase 2 trial was conducted to compare induction chemotherapy with docetaxel plus cisplatin and 5-fluorouracil (TPF) with cisplatin and 5-fluorouracil (PF) in NPC patients under the age of 21.