EML4-ALK-positive lung adenocarcinoma presenting an unusual metastatic pattern in a 29-year-old woman who is alive and well in her third year follow up: A case report


Tokat F. , Zeren H. , Barut P., Tansan S., Ince Ü.

RESPIRATORY MEDICINE CASE REPORTS, vol.22, pp.117-122, 2017 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22
  • Publication Date: 2017
  • Doi Number: 10.1016/j.rmcr.2017.07.008
  • Title of Journal : RESPIRATORY MEDICINE CASE REPORTS
  • Page Numbers: pp.117-122
  • Keywords: EML4-ALK translocation, Adenocarcinoma, Subcutaneous metastasis, CANCER

Abstract

Non-small cell lung cancer (NSCLC) is a frequent tumor entity with high mortality. Although several newly discovered chromosomal translocations and mutations opened new horizons for targeted therapy, literature still lacks large series of NSCLC with chromosomal abberations and their correlations with histological and clinical features. We present a case of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) translocation positive adenocarcinoma of the lung with an unusual metastatic pattern in a 29-year-old young woman.