EML4-ALK-positive lung adenocarcinoma presenting an unusual metastatic pattern in a 29-year-old woman who is alive and well in her third year follow up: A case report

Tokat F., Zeren H., Barut P., Tansan S., Ince Ü.

RESPIRATORY MEDICINE CASE REPORTS, cilt.22, ss.117-122, 2017 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.rmcr.2017.07.008
  • Dergi Adı: RESPIRATORY MEDICINE CASE REPORTS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.117-122
  • Anahtar Kelimeler: EML4-ALK translocation, Adenocarcinoma, Subcutaneous metastasis, CANCER
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Non-small cell lung cancer (NSCLC) is a frequent tumor entity with high mortality. Although several newly discovered chromosomal translocations and mutations opened new horizons for targeted therapy, literature still lacks large series of NSCLC with chromosomal abberations and their correlations with histological and clinical features. We present a case of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) translocation positive adenocarcinoma of the lung with an unusual metastatic pattern in a 29-year-old young woman.