Intrapleural hyperthermic perfusion chemotherapy in subjects with metastatic pleural malignancies


Isik A. F. , Sanli M., Yilmaz M., Meteroglu F., Dikensoy Ö., Sevinc A., ...More

RESPIRATORY MEDICINE, vol.107, no.5, pp.762-767, 2013 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 107 Issue: 5
  • Publication Date: 2013
  • Doi Number: 10.1016/j.rmed.2013.01.010
  • Journal Name: RESPIRATORY MEDICINE
  • Journal Indexes: Science Citation Index Expanded
  • Page Numbers: pp.762-767
  • Keywords: Malignant pleural effusion, Lung carcinoma, Hyperthermic perfusion chemotherapy, INTRATHORACIC CHEMOTHERAPY, LUNG-CANCER, MESOTHELIOMA, CISPLATIN, DISSEMINATION, DOXORUBICIN, APOPTOSIS, RESECTION, EFFUSION, SURGERY

Abstract

Objectives: Malignant pleural effusion (MPE) means poor prognosis in the majority of cases. Intrapleural Hyperthermic perfusion chemotherapy (HIPEC) looks promising approach for these patients. We aimed to investigate whether cytoreductive surgery followed by HIPEC provides any survival benefit in cases with metastatic MPEs.