In vitro bacterial adherence to teicoplanin and calcium sulfate-soaked bone cement

Sencan I., Sahin I., Tuzuner T. , Ozdemir D., Yildirim M., Leblebicioglu H.

JOURNAL OF CHEMOTHERAPY, vol.17, no.2, pp.174-178, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2005
  • Doi Number: 10.1179/joc.2005.17.2.174
  • Title of Journal : JOURNAL OF CHEMOTHERAPY
  • Page Numbers: pp.174-178


The aim of this study was to assess in vitro the improvement in release kinetics for teicoplanin and the inhibition of bacterial adhesion on calcium sulfate-soaked PMMA discs. Calcium sulfate has been used in vivo and shown to be biocompatible, and prevention of bacterial adhesion may be expected with calcium sulfate-soaked polymethylmethacrylate (PMMA). Discs were made by adding teicoplanin and calcium sulfate in powder form to PMMA powder.