WIRELESS fNIRS WITH SPATIALLY RESOLVED SHORT SEPARATION APPROACH FOR IMPROVED SNR

Tez Türü: Yüksek Lisans

Tezin Yürütüldüğü Kurum: Acıbadem Mehmet Ali Aydınlar Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, Biyomedikal Mühendisliği Bölümü, Türkiye

Tez Danışmanı: Prof. Dr. Ata Akın

Tezin Onay Tarihi: 2018

Tezin Dili: İngilizce

Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu

Özet:

In this project, ―Vega Vision‖ a wearable wireless functional near infrared spectroscopy (fNIRS) device was developed with a unique probe geometry. A spatially resolved high signal-to-noise ratio (SNR) device was designed by utilization of far/short detector probe (3/1.5cm separation) geometry and oversampling technique. Measurements were taken from non-smoking and smoking individuals during a head-tilt maneuver protocol. Total hemoglobin (TotHb) changes from resting to head down and from head down to up showed statistically different values: deviation of delta TotHb down between non-smokers and smokers was 33.2% (P=0.040) for the right half of brain and 35.4% (P=0.008) for the 4th channel from left end side, meanwhile deviation of delta TotHb up between non-smokers and smokers was 30.0% (P=0.040) for the right half of brain and 30.8% (P=0.015) for the 4th channel from left end side. In overall, the device designed proved to be a safe, affordable and easy-to-use fNIRS device suitable for clinical deployment.