Investigation of VEGF and IL-8 Gene Polymorphisms in Patients with Differentiated Thyroid Cancer

Kilic I., Guldiken S., Sipahi T., Palabiyik O., Akker M., Celik Ö., ...Daha Fazla

CLINICAL LABORATORY, cilt.62, sa.12, ss.2319-2325, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 12
  • Basım Tarihi: 2016
  • Doi Numarası: 10.7754/clin.lab.2016.160403
  • Dergi Adı: CLINICAL LABORATORY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2319-2325
  • Anahtar Kelimeler: differentiated thyroid cancer, angiogenesis, IL-8 gene polymorphism, VEGF gene polymorphism, ENDOTHELIAL GROWTH-FACTOR, CELL LUNG-CANCER, TUMOR ANGIOGENESIS, GASTRIC-CANCER, INTERLEUKIN-8 PROMOTER, POOLED ANALYSIS, INCREASED RISK, CARCINOMA, EXPRESSION, ASSOCIATION
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Background: Differentiated thyroid carcinomas (DTC) account for most of the thyroid cancers. The emergence of DTC may be affected by various predisposing genetic alterations and environmental factors The aim of this study was to investigate the role of VEGF C936T and IL-8 A251T gene polymorphisms in the pathogenesis and metastasis of differentiated thyroid cancer.