Neuroprotective effects of erythropoietin against oxidant injury following brain irradiation: an experimental study

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UĞURLUER G., Cebi A., Mert H., Mert N., Serin M., Erkal H. S.

ARCHIVES OF MEDICAL SCIENCE, cilt.12, sa.6, ss.1348-1353, 2016 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5114/aoms.2016.58622
  • Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1348-1353
  • Anahtar Kelimeler: brain, irradiation, oxidant injury, neuroprotective effects, erythropoietin, CENTRAL-NERVOUS-SYSTEM, RECOMBINANT-HUMAN-ERYTHROPOIETIN, RADIATION-INDUCED APOPTOSIS, OXIDATIVE-STRESS, RAT, MECHANISMS, PROTECTION, TOXICITY, RADICALS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Introduction: Radiation therapy (RT) is a major treatment modality, and the central nervous system is a dose-limiting organ in clinical RT. This experimental study aims to present the evaluation of the neuroprotective effects of erythropoietin (EPO) against oxidant injury following brain irradiation in rats.