Adding taxane to platin-5-fluorouracil combination does not improve survival rate in patients >= 65 years of age with advanced gastric cancer: A retrospective-multicenter study

Gunaldi M., Kose F., Demirci N. S., Gunduz S., Ozdemir N., Kocoglu H., ...Daha Fazla

JOURNAL OF BUON, cilt.23, sa.2, ss.416-421, 2018 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 2
  • Basım Tarihi: 2018
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.416-421
  • Anahtar Kelimeler: advanced gastric cancer, elderly, prognosis, survival, taxane, 1ST-LINE THERAPY, PHASE-III, OLDER, FLUOROURACIL, MANAGEMENT
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Purpose: Advanced gastric cancer (AGC) has a dismal prognosis. Platin-5-fluorouracil (CF) combination chemotherapy is the most widely used protocol and addition of a taxane (TCF) seems to increase survival and toxicity rates. We aimed to evaluate efficacy and toxicity of TCF as compared to CF in patients older than 65 years and compare them with the patients younger than 65 years.