GCK gene mutations are a common cause of childhood-onset MODY (maturity-onset diabetes of the young) in Turkey

HALİLOĞLU, BELMA; Hysenaj, Gerald; Atay, Zeynep; GÜRAN, TÜLAY; ABALI, SAYGIN; DEMİRCİOĞLU, SERAP; BEREKET, ABDULLAH; Ellard, Sian

doi:10.1111/cen.13121

GCK gene mutations are a common cause of childhood-onset MODY (maturity-onset diabetes of the young) in Turkey

HALİLOĞLU B., Hysenaj G., Atay Z., GÜRAN T., ABALI S., DEMİRCİOĞLU S., ...Daha Fazla

CLINICAL ENDOCRINOLOGY, cilt.85, sa.3, ss.393-399, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 85 Sayı: 3
Basım Tarihi: 2016
Doi Numarası: 10.1111/cen.13121
Dergi Adı: CLINICAL ENDOCRINOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.393-399
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

ObjectiveInactivating heterozygous mutations in the GCK gene are a common cause of MODY and result in mild fasting hyperglycaemia, which does not require treatment. We aimed to identify the frequency, clinical and molecular features of GCK mutations in a Turkish paediatric cohort.