Akademik Veri Yönetim Sistemi
CLINICAL IMAGING, cilt.68, ss.249-256, 2020 (SCI-Expanded, Scopus)
Purpose: With this study, we evaluated the perfusion magnetic resonance imaging (MRI) features of benign inflammatory breast lesions for the first time and compared their K-trans, K-ep, V-e values and contrast kinetic curves to benign masses and invasive ductal carcinoma (IDC). Materials and methods: Perfusion MRIs of the benign masses (n = 42), inflammatory lesions (n = 25), and IDCs (n = 16) were evaluated retrospectively in terms of K-trans,K- K-ep, V-e values and contrast kinetic curves and compared by the Kruskal-Wallis, Mann-Whitney U, chi-square tests statistically. Cronbach a test was used to measure intraobserver and interobserver reliability. Results: Mean K-trans, values were 0.052 for benign masses, 0.086 for inflammatory lesions and 0.101 for IDC (p < 0.001). Mean K-ep values were 0.241 for benign masses, 0.435 for inflammatory lesions and 0.530 for IDC (p < 0.001). Mean V-e values were 0.476 for benign masses, 0.318 for inflammatory lesions and 0.310 for IDC (p = 0.067). For inflammatory and IDC lesions, K-tran(s) and K-ep values were found to be higher and V-e values were lower than benign masses (p = 0.001 for K-trans p = 0.001 for K-ep, p = 0.045 for V-e). There were excellent or good infra-interobserver reliabilities. For the kinetic curve pattern, most of the benign lesions showed progressive (81%), inflammatory lesions progressive (64%) and IDC lesions plateau (75%) patterns (p < 0.001). Conclusions: On T1 perfusion MRI, similar to IDC lesions, inflammatory lesions demonstrate higher K-tran(s) and K-ep and lower V-e values than benign masses. Quantitative perfusion parameters are not helpful in differentiating them from IDC lesions.