The effect of serum levetiracetam concentrations on therapeutic response and IL1-beta concentration in patients with epilepsy
EPILEPSY RESEARCH, cilt.148, ss.17-22, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 148
- Basım Tarihi: 2018
- Doi Numarası: 10.1016/j.eplepsyres.2018.09.015
- Dergi Adı: EPILEPSY RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.17-22
- Anahtar Kelimeler: Antiepileptic drugs, Seizure frequency, Adverse effect, Cytokine, ANTIEPILEPTIC DRUGS, ILAE-COMMISSION, CHILDREN, LAMOTRIGINE, EFFICACY
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır
Özet
Objective: Assessment of the relevance between serum drug concentration to its therapeutic response is a valid monitoring strategy for the clinical efficacy of antiepileptic drugs (AEDs). Levetiracetam (LEV) is a broad spectrum AED with a possible anti-inflammatory effect. We aimed to determine the relationship between LEV concentrations and its therapeutic response, and the effect of LEV on IL1-beta concentrations in patients with epilepsy.