Akademik Veri Yönetim Sistemi
ACTA MEDICA MEDITERRANEA, cilt.31, sa.1, ss.31-37, 2015 (SCI-Expanded, Scopus)
Aims: To investigate the role of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the evaluation of progressive massive fibrosis and centrilobular nodules in patients who had silicosis due to denim sandblasting. Materials and methods: Thirty-seven progressive massive fibrosis lesions and three centrilobular nodules were evaluated in 33 patients. The kinetic curves of each of the lesions on DCE-MRI was obtained; signal intensities on T2 weighted images were evaluated, along with the contrast characteristics of progressive massive fibrosis lesions and the correlation between the progressive massive fibrosis load and the diameter of the pulmonary arteries. Results: Progressive massive fibrosis tended to develop earlier in this subtype of silicosis. The visibility of progressive massive fibrosis on MRI compared to computed tomography was higher than that of centrilobular nodules. While DCE-MRI showed gradual contrast enhancement and no washout pattern for progressive massive fibrosis, centrilobular nodules had an earlier and higher maximum peak with a washout pattern. The degree of fibrosis was not correlated with the contrast values and a more progressive massive fibrosis load was associated with a greater degree of pulmonary vascular dilatation. Conclusions: MRI should be used in the evaluation of silicosis, especially in patients who have progressive massive fibrosis, because it is better at characterizing tissues and can be repeated without the danger of exposing the patient to radiation.