Efficacy of Palbociclib and Endocrine Treatment in Heavily Pretreated Hormone Receptor-positive/HER2-negative Advanced Breast Cancer: Retrospective Multicenter Trial

Demir, Atakan; Mandel, Nil; PAYDAŞ, SEMRA; Demir, Gokhan; ER, ÖZLEM; Turhal, Nazim; Bavbek, Sevil; Eralp, YEŞİM; Saip, Pinar; Guler, Emine; Aydiner, Adnan; OYAN ULUÇ, BAŞAK; Kilickap, Sadettin; Uskent, Necdet; Karadurmus, Nuri; Kaplan, Mehmet; Yanmaz, Mustafa; Demir, Hacer; Alan, Ozkan; KORKMAZ, TANER; Olgun, Polat; Uysal, Ozlem; Altundag, Kadri; Gunduz, Seyda; Gunaldi, Meral; Sari, Murat; Beypinar, Ismail; BAŞARAN, GÜL

doi:10.4274/balkanmedj.galenos.2020.2019.11.143

Efficacy of Palbociclib and Endocrine Treatment in Heavily Pretreated Hormone Receptor-positive/HER2-negative Advanced Breast Cancer: Retrospective Multicenter Trial

Demir A., Mandel N. M., PAYDAŞ S., Demir G., ER O., Turhal N. S., ...Daha Fazla

Balkan medical journal, cilt.37, sa.2, ss.104-107, 2020 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 37 Sayı: 2
Basım Tarihi: 2020
Doi Numarası: 10.4274/balkanmedj.galenos.2020.2019.11.143
Dergi Adı: Balkan medical journal
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.104-107
Anahtar Kelimeler: Breast cancer, CDK4/6 inhibitors, palbociclib, COMBINATION, RESISTANCE, LETROZOLE
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Background: The synthesis of CDK4/6 inhibitors with endocrine treatment in two series of treatment has been widely accepted as the standard for patients with estrogen receptor-positive metastatic breast cancer. In spite of this, the activity of CDK4/6 inhibitors in patients with metastatic breast cancer who have progressed despite receiving multiple lines of treatment is not well understood.