FRONTIERS IN ENDOCRINOLOGY, vol.9, 2018 (Journal Indexed in SCI)
Article / Article
Title of Journal :
FRONTIERS IN ENDOCRINOLOGY
NIS inhibitors, perchlorate, nitrate, thiocyanate, colostrum, newborn thyroid health, SODIUM-IODIDE SYMPORTER, BOSTON-AREA WOMEN, PREGNANT-WOMEN, DRINKING-WATER, BREAST-MILK, THIOCYANATE, NITRATE, CALIFORNIA, ORIGIN, NIS
Background: Perchlorate, thiocyanate, and nitrate can block iodide transport at the sodium iodide symporter (NIS) and this can subsequently lead to decreased thyroid hormone production and hypothyroidism. NIS inhibitor exposure has been shown to reduce iodide uptake and thyroid hormone levels; therefore we hypothesized that maternal NIS inhibitor exposure will influence both maternal and newborn thyroid function.