Clinical importance of "low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion (LSIL-H)" terminology for cervical smears 5-year analysis of the positive predictive value of LSIL-H compared with ASC-H, LSIL, and HSIL in the detection of high-grade cervical lesions with a review of the literature.

Ince Ü., Aydin Ö., Peker O.

Gynecologic oncology, vol.121, no.1, pp.152-6, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 121 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1016/j.ygyno.2010.12.004
  • Journal Name: Gynecologic oncology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.152-6
  • Keywords: Cervical smear, Pap test, Bethesda System, Diagnostic category, Squamous intraepithelial lesion (SIL), Cervical intraepithelial neoplasia (CIN), CONSENSUS GUIDELINES, BETHESDA SYSTEM, DIAGNOSIS, CATEGORY, CELLS, MANAGEMENT, OUTCOMES, TESTS, WOMEN, RULE
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Objective. We compared follow-up biopsy findings and positive predictive values (PPVs) for cervical intraepithelial neoplasia 2 or worse (CIN 2+) in cases that were cytologically interpreted as low-grade squamous intraepithelial lesions (LSIL); high-grade squamous intraepithelial lesions (HSIL); LSIL, cannot exclude HSIL (LSIL-H); and atypical squamous cells, cannot exclude HSIL (ASC-H) during a 5-year period to evaluate the clinical significance of LSIL-H as a distinct cytological category.