The importance of brain banking for dementia practice: the first experience of Turkey

IŞIK A. T., ERŞEN DANYELİ A., KAYA D., SOYSAL P., KARABAY N., Gokden M.

CELL AND TISSUE BANKING, cilt.21, sa.3, ss.367-375, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1007/s10561-020-09835-2
  • Dergi Adı: CELL AND TISSUE BANKING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, CINAHL, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.367-375
  • Anahtar Kelimeler: Brain banking, Neurodegenerative diseases, Dementia, Brain donation, Brain autopsy, ALZHEIMERS-DISEASE, NATIONAL INSTITUTE, DIAGNOSIS, GUIDELINES, MANAGEMENT, DISORDERS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

This study reports the results of the first brain tissue banking experience of Turkey in the Unit for Aging Brain and Dementia at Dokuz Eylul University, Department of Geriatric Medicine, Izmir. Here, we have briefly described our efforts on brain banking in our country, which consist of six brains from autopsies that had at least two years of clinical follow-up in the 2015-2017 period. The evaluation led to the diagnosis of two Alzheimer's disease (AD) with cerebral amyloid angiopathy, one AD with dementia with Lewy bodies, one corticobasal degeneration, one multiple system atrophy, one vascular dementia. We believe that the study is of a special importance because of its potential of becoming a brain banking center in the region and because of its contributing to the international knowledge of the neuropathological features of dementia, while characterizing the epidemiology of these diseases in the region.