Serum M65 as a biomarker for metastatic renal cell carcinoma.

YILDIZ İ., Sen F., Kilic L., Keskin S., DURANYILDIZ H. D., Bilgin E., ...Daha Fazla

Clinical genitourinary cancer, cilt.11, sa.3, ss.290-6, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.clgc.2013.01.001
  • Dergi Adı: Clinical genitourinary cancer
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.290-6
  • Anahtar Kelimeler: Serum M65 level, Apoptosis, Cytokeratin 18, Kidney cancer, Prognostic factors, CASPASE-CLEAVED CYTOKERATIN-18, LUNG-CANCER, MONOCLONAL-ANTIBODIES, DEATH, M30, REORGANIZATION, FRAGMENTS, DIAGNOSIS, ANTIGENS, PRODUCT
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

We aimed to investigate the prognostic significance of M30 and M65 which are biomarkers of apoptotic cell death in renal cell cancer (RCC). Serum levels of M30 and M65 were analyzed in 39 consecutively enrolled patients with metastatic RCC and control subjects using enzyme-linked immunosorbent assay (ELISA) kits. We found that high serum M65 levels might predict worse outcome resulting in shorter progression-free survival in RCC.