Leishmaniasis in Turkey: Determination of Leishmania Species by Matrix-Assisted Laser Desorption Ionization Time-Of-Flight Mass Spectrometry (MALDI-TOF MS)

ÇULHA G., AKYAR I., Zeyrek F. Y., KURT Ö., GÜNDÜZ C., TÖZ S., ...Daha Fazla

IRANIAN JOURNAL OF PARASITOLOGY, cilt.9, sa.2, ss.239-248, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 2
  • Basım Tarihi: 2014
  • Dergi Adı: IRANIAN JOURNAL OF PARASITOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.239-248
  • Anahtar Kelimeler: Cutaneous leishmaniasis, Leishmania infantum, Turkey, Real-Time PCR, MALDI-TOF, WORLD CUTANEOUS LEISHMANIASIS, GENETIC-HETEROGENEITY, INTACT MICROORGANISMS, RAPID IDENTIFICATION, PROTEOMIC APPROACH, BACTERIA, DIAGNOSIS, EPIDEMIOLOGY, POLYMORPHISM, PROTEINS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Background: Cutaneous leishmaniasis (CL) is endemic in Southeastern Anatolia, mainly in Sanliurfa and Hatay provinces, and the causative agents are mostly Leishmania tropica and less frequently L. infantum. Here, we report the first MALDI-TOF analyses of Leishmania promastigotes obtained from the cultures of two CL cases from Osmaniye and Hatay provinces who were initially diagnosed by microscopy, culture and identified as L. infantum with Real-Time PCR (RT-PCR).