Effects of developmental exposure to silver in ionic and nanoparticle form: A study in rats

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Charehsaz M., Hougaard K. S., Sipahi H., Ekici A. I., Kaspar C., Culha M., ...Daha Fazla

DARU-JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.24, 2016 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1186/s40199-016-0162-9
  • Dergi Adı: DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Silver, Oxidative stress, Hippocampal sclerosis, Pregnancy, Rat, IN-VIVO, POSSIBLE MECHANISM, SPATIAL COGNITION, PRENATAL EXPOSURE, OXIDATIVE STRESS, TOXICITY, BRAIN, VITRO, MICE, NEURODEVELOPMENT
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: Evaluations of silver in both nanoparticle (Ag-NPs) and ionic forms indicate some adverse effects on living organisms, but little is known about their potential for developmental toxicity. In this study, developmental toxicity of Ag-NPs (from 0.2 to 20 mg/kg/day) and ionic Ag (AgNO3, 20 mg Ag/kg/day) were investigated in rats.