Pharmacologically induced absence seizures versus kindling in Wistar rats

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Carcak N., Sahiner M., Akman O., Idrizoglu M. G., Cortez M. A., Snead O. C., ...More

NORTHERN CLINICS OF ISTANBUL, vol.7, no.1, pp.25-34, 2020 (ESCI, TRDizin) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.14744/nci.2019.80664
  • Journal Name: NORTHERN CLINICS OF ISTANBUL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.25-34
  • Keywords: Amygdala, gamma-butyrolactone, experimental limbic epilepsy, genetic absence epilepsy, kindling, GAMMA-HYDROXYBUTYRATE MODEL, ELECTRICAL-STIMULATION, ANIMAL-MODELS, EPILEPSY, BRAIN, BUTYROLACTONE, ACID, MECHANISMS, RESISTANCE, INJECTION
  • Open Archive Collection: AVESIS Open Access Collection
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

OBJECTIVE: This study aimed to investigate the effects of gamma-butyrolactone (GBL), a prodrug of gamma-Hydroxybutyric acid-induced absence seizures on the development of kindling in Wistar rats.